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Thursday, August 6, 2020 | History

1 edition of Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse found in the catalog.

Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse

Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse

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  • 1 Currently reading

Published by U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Institute on Drug Abuse in Rockville, MD .
Written in English

    Subjects:
  • Drugs of abuse -- Metabolism.,
  • Drugs of abuse -- Metabolic detoxification.,
  • Drugs of abuse -- Pharmacokinetics.,
  • Street Drugs -- metabolism,
  • Street Drugs -- pharmacokinetics.,
  • Substance Abuse.

  • Edition Notes

    Includes bibliographical references.

    Statementeditors, Rao S. Rapaka, Nora Chiang and Billy R. Martin.
    SeriesNIH publication ;, no. 97-4141, NIDA research monograph ;, 173, National Institute on Drug Abuse research monograph series ;, 173.
    ContributionsRapaka, Rao S., Chiang, C. Nora., Martin, Billy R., National Institute on Drug Abuse
    Classifications
    LC ClassificationsRM316 .P47 1997
    The Physical Object
    Paginationiv, 316 p. :
    Number of Pages316
    ID Numbers
    Open LibraryOL296775M
    LC Control Number97203049
    OCLC/WorldCa37358430

    increased drug metabolism, that decrease the concen-trations achieved with a given dose. There can also be pharmacodynamic tolerance, which occurs when the same concentration at the receptor site results in a reduced effect with repeated exposure. An example of drug tolerance is the use of opiates in the management of chronic pain. Drugs of abuse -- Metabolism. See also what's at your library, or elsewhere.. Broader terms: Drugs of abuse; Metabolism; Filed under: Drugs of abuse -- Metabolism Pharmacokinetics, Metabolism, and Pharmaceutics of Drugs of Abuse, ed. by Rao S. Rapaka, C. Nora Chiang, and Billy R. Martin (PDF files at NIH); Items below (if any) are from related and broader terms.

      He has more than 50 publications in the field of pharmacokinetics and clinical pharmacology, is co-editor of the 3-volume series Pharmacokinetics in Drug Development published by AAPS Press in and , and is author of the book Pharmacokinetic-Pharmacodynamic Modeling and Simulation published by Springer in In , he became an.   Book Description. Extracted from the Drug Abuse Handbook, 2 nd edition, to give you just the information you need at an affordable price.. Pharmacokinetics and Pharmacodynamics of Abused Drugs is a concise and focused volume devoted to the metabolism and measurable effects of drugs on the human body. Beginning with basic concepts and models designed to provide a .

    Download Pharmacokinetics; Metabolism and Pharmaceutics of Drugs of Abuse: Edition in pdf format by Rapaka. The pharmacokinetics of a drug can generally be subdivided into the invasion phase (drug release, absorption), the distribution phase and the elimination phase (metabolism, excretion).


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Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse Download PDF EPUB FB2

Pharmacokinetics, Metabolism, and Pharmaceutics of Drugs of Abuse Editors: Rao S. Rapaka, Ph.D. Division of Basic Research National Institute on Drug Abuse Nora Chiang, Ph.D. Medications Development Division National Institute on Drug Abuse and Billy R.

Martin, Ph.D. Department of Pharmacology Virginia Commonwealth University NIDA Research. Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse Paperback – January 1, Anonymous. Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse.

Rockville, MD: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Institute on Drug Abuse, (OCoLC) Material Type: Government publication, National government publication, Internet resource: Document Type.

Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse. Rockville, MD: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Pharmacokinetics, National Institute on Drug Abuse, (DLC) (OCoLC) Material Type: Document, Government publication, National government publication, Internet resource.

The Online Books Page Pharmacokinetics, Metabolism, and Pharmaceutics of Drugs of Abuse. Pharmacokinetics and Metabolism in Drug Design: While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects.

Report abuse. Translate review to s: 2. Drug Metabolism and Pharmacokinetics Quick Guide is intended for broad readership of those interested in the discipline of drug metabolism and pharmacokinetics who work in drug discovery coming from the various disciplines, a background such as of medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics or.

Pharmaceutics for the design and development of new dosage forms to improve their therapeutic Pharmacokinetics and/or to minimize the abuse potential of potential treatment medications.

Pharmacokinetics (PK) and pharmacodynamics of potential treatment medications. Pharmacogenetics to investigate the genetic variability affecting pharmacokinetics. In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.

Evaluation of Drug Candidates for Preclinical Development por Chao Han,disponible en Book Depository con envío gratis. European Journal of Drug Metabolism and Pharmacokinetics offers a range of additional features designed to increase the visibility, readership and educational value of the journal’s content.

Each article is accompanied by a Key Points summary, giving a time-efficient overview of the content to a wide readership. He has more than 40 publications in the field of pharmacokinetics and clinical pharmacology, is co-editor of the 2-volume series Pharmacokinetics in Drug Development published by AAPS Press inand is author of the book Pharmacokinetic-Pharmacodynamic Modeling and Simulation published by Springer in pharmacokinetics and drug metabolism departments, but also for other discovery and development groups in pharmaceutical companies.

This book is designed specifically for industrial scientists, laboratory assistants, and managers who are involved in PK/PD/DM-related areas. It consists of. Pharmacokinetic determinants of drug abuse and dependence.

A conceptual perspective. Busto U, Sellers EM. Drugs that produce physical dependence or have similar pharmacological profiles to highly abused drugs are unlikely to be considered acceptable for marketing. Thus, this book is aimed at all those dealing professionally with the development and application of pharmaceutical substances.

Furthermore, the readily comprehensible style of writing makes it equally suitable for students of pharmacy and related subjects, who feel that pharmacokinetics is covered too briefly in the standard textbooks.

The UWPKDAP (U niversity of W ashington Program on P harmacokinetics of D rugs of A buse during P regnancy) is an NIH (NIDA)-funded research program in the Department of Pharmaceutics, School of Pharmacy at the University of primary purpose of the program is to elucidate the fundamental mechanisms of maternal-fetal drug disposition in pregnant women with special emphasis.

Drug Metabolism and Pharmacokinetics Quick Guide is intended for broad readership of those interested in the discipline of drug metabolism and pharmacokinetics who work in drug discovery coming from the various disciplines, a background such as of medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics or Reviews: 2.

It is believed that selecting the "right" drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds.

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians.

Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and.

Dennis Smith has worked in the pharmaceutical industry for the past 30 years since gaining his Ph.D. from the University of Manchester. For the last 18 years he has been at Pfizer global research and Development, Sandwich where he is vice President-Pharmacokinetics, Dynamics and Metabolism.

Pharmacokinetics is a study of drug and metabolite kinetics in the body: drug absorption, distribution, metabolism, and excretion. Pharmacokinetic models and mathematic models are used to calculate drug dosage regimens, perform dosage adjustments in patients, predict food–drug and drug–drug interactions, design and test drug formulations and novel drug delivery systems, and evaluate the.

Buy Pharmacokinetics and Metabolism in Drug Design While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects.

Report abuse. Translate review to s: 2.Title:Pharmacokinetics-Pharmacology Disconnection of Herbal Medicines and its Potential Solutions with Cellular Pharmacokinetic-Pharmacodynamic Strategy VOLUME: 13 ISSUE: 5 Author(s):Jingwei Zhang, Fang Zhou, Meng Lu, Wei Ji, Fang Niu, Weibin Zha, Xiaolan Wu, Haiping Hao and Guangji Wang Affiliation:Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University.